Everything You Need to Know About the Panthers vs 49ers

The Carolina Panthers play host to the San Francisco 49ers in week five, the second of four meetings against NFC West opponents in 2022.

The Panthers enter the week 1-3 after falling to the Arizona Cardinals at home by a score of 26-16. San Francisco travels to the east coast with a record of 2-2 after defeating the Los Angeles Rams by a score of 24-9 on Monday night.

This will mark the 23rd overall match up against the 49ers, and 12th at home. Carolina enters the game with a lead in the series – 13-9 overall, including 6-5 as the home team. The Panthers and 49ers were previously division foes in the NFC West from 1995 to 2001.

The Numbers

About Carolina

About San Francisco

Connections

Photo: Angela Denogean/Carolina Panthers

Panthers vs 49ers

All-Time Series (21 Regular, 1 Postseason): 22 total matchups | Carolina leads the series 13-9

Last Regular Season Game: 10/27/19 | Panthers 13 @ 49ers 51

Series Record at Venue: Carolina is 6-5 in home games against San Francisco

How to Watch

Kickoff: 4:05 p.m. ET FOX – Ian Eagle, Charles Davis, Evan Washburn

Live Stream: Panthers.com

Radio: WRFX 99.7FM in Charlotte market; On The Call: Anish Shroff, Jake Delhomme, Luke Kuechly, Kristen Balboni, Jim Szoke

Per Release

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